The 14th Five Year Plan clearly proposes to promote the deep integration of modern service industry with advanced manufacturing industry and modern agriculture, and accelerate the digitization of service industry. Stabilizing and optimizing the construction of the Chengdu-Chongqing Double-city Economic Circle is a major measure to build a dual cycle strategic layout. Improving the level of industrial integration and development not only provides a solid foundation for enhancing the international competitiveness of industries in Chengdu-Chongqing region, but also provides an important path for accelerating the overall upgrading of the "dual circulation" industrial chain. The article first uses the entropy weight method and the modified model of coupling coordination degree model to evaluate the development level of the primary, secondary, and tertiary industries in the Chengdu-Chongqing Double-city Economic Circle from 2010 to 2020, as well as the coupling coordination level between industrial systems, and characterizes its spatiotemporal distribution pattern. Further, the paper constructs a panel data model to comprehensively test the dynamic factors that affect the industrial integration and development of Chengdu Chongqing Double-city Economic Circle. The research results show that: firstly, the overall level of industrial development in the Chengdu-Chongqing Double-city Economic Circle is on the rise, with relatively low agricultural index, stable industrial development and significant increase in service industry index. Secondly, within the study area, the development level of Chengdu-Chongqing Double-city Economic Circle industrial integration is concentrated between 0.30 and 0.49, and the overall coordination degree is low. The distribution range of regions with high levels of industrial integration and development has evolved from north to south, gradually becoming a "ring". Thirdly, technological progress, talent resources, and infrastructure are positively driving the integration and development of industries in the Chengdu-Chongqing Double-city Economic Circle. Market demand, fiscal finance, and foreign trade are underutilized as drivers influenced by the fragmentation of administrative power. In response to the above issues, the article proposes policy recommendations from accelerating the construction of regional market integration, enhancing the modernization level of the industrial chain, and improving industrial regional cooperation mechanisms.