Since the 18th National Congress of the Communist Party of China, General Secretary Xi Jinping has led the Party to promote full and strict governance over the Party with unprecedented determination and strength, creatively proposing a series of original and iconic new concepts, new ideas, and new strategies, forming General Secretary Xi Jinping's important thoughts on the Party's self-reform. The important thoughts on the Party's self-reform is the new achievement of the Party in promoting theoretical innovation by combining the basic principles of Marxism with China's specific realities, and with China's excellent traditional culture. It is an important part of the scientific system of Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era. The origin and evolution of the concept of revolution to self-revolution from the perspectives of Chinese and Western civilizations reflect the historical cyclicality of societal rise and fall. Diverging from the traditional Western bourgeois notion of revolution as a social movement aimed at dismantling old political structures and establishing new social orders, self-revolution inherits Marxist principles of restructuring economic systems, emphasizing that revolutionary subjects undergo transformative processes driven by internal causes. The Party's self-reform aligns closely with the ideals and connotations found in excellent traditional Chinese culture, such as reforming the past and renewing the future, introspection and self-discipline, the people as the foundation of a nation, and righteousness and obedience. The courage to engage in self-reform represents a distinctive characteristic of the Communist Party of China, reflecting its profound cultural confidence. General Secretary Xi Jinping delivered important speeches at the third plenary session of the 20th Central Commission for Discipline Inspection, clearly put forward the practical requirements of "nine takings", and made a strategic deployment of continuous efforts and deep promotion of anti-corruption campaign. The requirements of "nine takings" are not only macro-level objectives, tasks, top-level designs, but also detailed implementation methods that highlight key aspects. Epistemology and methodology are both integral components here. Looking at "the second answer" from "the second combination", we can comprehend the theoretical connotations and practical approaches of the important thoughts on the Party's self-reform. It is crucial to grasp the significant innovative viewpoints, scientific methodologies, as well as the strategic arrangements contained within Xi Jinping's important thoughts on the Party's self-reform while consciously leading great social reforms with great self-reform from the perspective of "the second combination".