The international communication of philosophy and social sciences with Chinese characteristics is an important part of the construction of the Chinese modern international discourse system, and also the due meaning of improving China's international communication ability and international discourse power. The construction of China's independent knowledge system is not only a practical necessity to promote Chinese modernization and realize the great rejuvenation of the Chinese nation, but also a theoretical requirement to contribute to the global knowledge system the Chinese wisdom and experience that can be stated, established and disseminated. The independent knowledge system based on the three major systems is the origin of the international communication of Chinese philosophy and social sciences. Without China's independent knowledge system, there is no foundation for enhancing the dissemination and influence of Chinese civilization, and the international communication is like water without a source or a tree without roots. The unity of independence and embeddedness, value relevance and value independence is the theoretical form that the international communication of Chinese philosophy and social sciences should possess. However, at present, comparing with Harvard University's Fei Zhengqing Center for China Studies, it can be found that the international communication of philosophy and social sciences with Chinese characteristics still has many problems, including insufficient research on the international communication object, lagging behind of international communication media and channel construction, insufficient setting of international communication agenda, and imperfect funding and control system of international communication. In this regard, suggestions are proposed from the dimensions of constructing an independent knowledge system with Chinese characteristics embedded in the world, and constructing an international communication system of philosophy and social sciences with Chinese characteristics that is more suitable for communication.