The selection of leading industry plays an important role to the development of regional central cityThe anthors combine the concrete conditions of Chongqing and realistic economic conditions on the basis of absorbing western leading industry's theory, structure and include the demand income elasticity , influence power coefficient, reaction degrees of coefficient , technical progress rate, technological progress contribution rate ,etc, total thirteen indexes on leadingindustrial and apply them to Chongqing, calculate the relevant indexes of the existing main industrial sector of Chongqing separately, at last, use Using distinguish model of artificial neural network to confirm the leading industries of Chongqing 