The paper adopted revised entrepreneurial burnout scale and social support scale and investigated 215 sample of entrepreneur. The formal survey data were returned and analyzed the relationship between social support and burnout by correlate analysis and regression analysis. The result indicated that the social support was four-factor construct model; the four factors referred to information support, emotion support, instrument support and feedback support. Information support, emotion support, instrument support of the social supports had significant correlation with emotional exhaustion, entrepreneurial achievement, and entrepreneurial identification. One the other hand, the paper indicated that social support had significant predicting effect on burnout. One dimension of support had stronger effect than multiple dimensions of social support on burnout.