Under the background of informatization in China, regional E-government readiness index evaluation system is built on the basis of administrative ecology concept through empirical analysis of E-government readiness of 31 provinces, autonomous regions and municipalities. We find that there is a large difference in E-government readiness of different areas, and the E-government readiness scores tend to reduce from east to west, and all areas have a strong hardware, but the environment foundation is very weak. At last, it is suggested to strengthen the development of social informatization from three aspects: economic basis, communication infrastructure and human capital construction.