In study of the explicit characterization of creative industrial cluster, it can be found that knowledge sharing activity has great influence in this area. In this article, author constructs a creative industries cluster knowledge sharing decision-making multi-stage game model. By analyzing this model,the author finds multiple factors of creative industrial clusters of enterprises to implement knowledge sharing which include the knowledge sharing of development costs, absorptive capacity factor, enterprise knowledge sharing knowledge capacity of the market, enterprise cooperation before the share market effect coefficient and cost coefficient of knowledge sharing, cooperation, and each factors of knowledge sharing has a different mechanism. Through knowledge sharing, the product equilibrium price can be promoted. But whether to promote the profit of the enterprise depends on knowledge sharing market capacity change brought for the enterprise and R&D cost reduction and knowledge sharing cost comprehensively.