In constructing "double first-class" universities with Chinese characteristics, it is necessary to analyze the logical basis of running a school in China from the perspective of academics, in order to find an effective construction path. On the basis of investigating the historical rule of the rise of foreign universities to world-class universities, it is believed that the inheritance of outstanding national culture is the deep-rooted gene of building a "double first-class" university with Chinese characteristics. Responding to the national strategy is the internal demand of building a "double first-class" university with Chinese characteristics. The "Chinese Dream" of national rejuvenation is the sacred mission of building a world-class university. Building a discipline system with Chinese characteristics is a strong support for building a "double first-class" university. Therefore, the path choice for taking root in China to build a "double first-class" university with Chinese characteristics should be:taking moral education as the fundamental task of university reform and development, inheriting the innovating national culture as the spiritual core of university reform and development, serving the national strategy as the fundamental pursuit of university reform and development, running education to the satisfaction of the people as the self-conscious goal of university reform and development, and the construction of first-class disciplines and first-class teachers as an important starting point for university reform and development.