Abstract:He Jiankui's gene editing infant incident stirred up a thousand waves, which triggered the attention of the media and people from all walks of life at home and abroad. The doubts are generally out of grief for the future of mankind, focusing on the issues such as ethics and morality, human structure, social order breakthroughs and nuisances. This article takes this incident, as a perspective to explore the underlying causes of the outbreak of the incident, from the standpoint of Marxism, to analyze the post-humanism representation of science and technology combining to human beings as well as what human kind should do to face its constant occurance and how to adjust itself when post-humanism becomes an irresistible trend. Post-humanism takes the development of science and technology as the first traction and has an impact on the item of human being. This the involves the consciousness of "human" under the vision of science and technology and the ontological issue of human physical boundary and self-identity, which covers anthropology, sociology, ethics and other fields. The continuous fermentation of genetically edited infant event reminds humans that we must address this realistic and theoretical problem and rewrite the outline of "human". This article will focus on the dimension of critique of Marxist philosophy, the story core of Black Mirror, and combine the genetic editing infant event. By analyzing the presentation of the relationship of "You-It" and "He-It", it will be explained that characteristics of the post-human society is the subjectivity and generalization of science and technology, in which the beings show up with conscious and physical cybernetic characteristics. This article hopes to provide some insights for tackling the ultimate arrival of post-human society and the organic realization revealing of underline awareness of the "I-It" relationship.