Aimed at the problem of the in partial section of the Nanjing Metro Line 3, the three-dimensional pattern of tunnel, segment and pile foundation was established after appropriate simplification. The simulation results showed that, the Overpass pile foundation of Shield Tunneling to Adjacent Metro Shield Tunnel will have effect on the force and deformation of the earth's surface and pile foundation, the maximum deformation value of the earth's surface is larger than that of the pile foundation top, stress concentration appeared in right working slope lower side segment of tunnel. Through the comparison with field monitoring results, the field dates is consistent with the Numerical Simulation Results, the execution parameters are advised to be well controlled in the further construction, in the same time strengthing the track monitoring, tracking grouting reinforcement should be carried when necessary. The research results could provide reference for the smooth going of the project.