It is known that cylinder heads, exhaust manifoids, ingot molds, etc. are often failed resulting from thermal fatigue. For this reason, the influence of RE on the thermal fatigue behavior of cast iron was studied by measn of a thermal fatigue test unit with completely constrained strain developed by ourselves. The test results shown that RE can improve the thermal fatigue resistance of cast iron greatly when residual RE contents surpass a critical value. This value is 0.04-0.045% for light Rare-Earth, and 0.045-0.05%; for heavy Rare-Earth. Further more, the relationship between RE and the thermophysical and mechanical properties of cast iron which have influence on thermal fatigue resisteance was also discussed.