Ultra High Molecular Weight Polyethylene (UHMW-PE) is a kind of high anti-wear engineering plastic with many excellent physical and mechanical performances. It has been widely applied in the field of mechanism such as bearing and pump. Effect of load, speed, time on friction and wear properties of Ultra High Molecular Weight Polyethylene(UHMW-PE)plastic alloy bearings under different Lubricating Condition are studied by using MPV-200 model friction and wear testing machine. The test results show that water lubrication reduces the friction coefficient of bearings but increases the wear rate as compared with dry friction. At the same time, wear mechanisms are analyzed systemically. It provides a theoretic basic for practical application of plastic alloy bearings