Abstract:The process of actin polymerization and depolymerization have some relation with its function,the activation of such process is compatible to its functions. The polymerization progress is divided into four steps: The first step is the activation of the monomer actin. The nucleation of actin nucleus forms in the second step which limits the polymerization speed. The elongation of the F-actin filaments happens in the following step. In the last step, a steady-state is attained, the length of the filament does not change because the polymerizing rate in the barbed end is the same with the depolymerizing rate in the pointed end. Some factors which affect the polymerizing process, such as nucleotide, actin related proteins are discussed. The aim is to know more about how to assemble the complicated system with biomacromolecule and what to function.