Abstract:Chaos controlbased disease control has become a new direction for medical research. Chaos control can improve the study of nervous system diseases. To explain the inherent characteristics of such treatment with neurophysiology, a neuron dynamic simulation model, based on the Chay model, was built with MATLAB/SIMULINK. Various stimulations were inserted to analyze the dynamic change of the neuron action potential and its chaos expression. The experimental results show that different internal and external stimulations to the nervous system have great influence on membrane potential and chaos expression, indicating the importance and feasibility of chaos control in disease control.