Using precise design principle, a multi-objective programming mathematical model of the BOF-Caster matched is established for single production line in the steelmaking plant of all plate and strip, according to the segmentation of steel grade and product specification of product mix. Objectives of the model have less investment, less difference between production capacity of the converter and continuous caster, higher operating rate of converter and higher level of weighted average casting speed. The model is solved by the improved delaminating sequence method. Then, the overall configuration method of BOF-continuous casting in the steelmaking plant is proposed through integrating single production lines. According to the production outline of a new large steel plant, the result of the model shows that the configuration scheme of the steelmaking workshop of the steel plant is a better design scheme.