Spherical titania (TiO2) with narrow size distribution and nice dispersibility has been obtained by hydrolysis in the mixed solvent of 1-propanol to de-ionized water using microwave as heat source. Parameters like precursor concentration, heating method, microwave power, and pH value have been investigated. The results show that the high quality TiO2 can be synthesized using PVP as surfactant when the volume ratio of 1-propanol to de-ionized water is 1DK〗∶1. The results display that size and size distribution of the particles are affected by heating method, precursor concentration and pH value. However, the effect of microwave power is comparatively less obvious.