To prevent the duty cycle loss of full-bridge converter controlled by the phase-shifting method, a high frequency high voltage X-ray power supply is proposed. It combines full bridge LLC(FB-LLC) series resonant converter with bipolar single-phase symmetrical voltage multiplier. FB-LLC series resonant, high voltage transformer and bipolar single-phase symmetrical voltage multiplier are used in the main circuit. The LLC series resonant circuit and working conditions of soft switch are analyzed. The fundamental harmonic approximation model is established. The parameters of the main circuit are designed. The simulation results show that the output voltage adjusted continuously within 40~120 kV and without duty cycle loss. The X-ray power supply is proposed to achieve a quick rise and low ripple of output voltage. According to the simulation results, the proposed topology is correct and reliable.