Based on the heterogeneity of cable bundles and the randomness of wire spacing in cable bundles, this paper adopts the statistical theory to explore a method to predict the uneven cable bundle crosstalks. Under the assumption of electrically small and weak coupling, the mean value and standard deviation of the near end crosstalk voltage ratio are derived. 273RDSI numerical simulations are used to predict worst case crosstalk and to test the model effectiveness . The difference of the wire number and the bundles height from the ground are analyzed. The results indicate that for a given number of wires by increasing the bundle height the mean value increases, whereas the standard deviation is substantially independent of height. Moreover, the standard deviation decreases with the number of sections. By increasing the number of wires, both the mean value and the standard deviation decrease, whereas the sensitivity of the mean value to the bundle height increases.