The numerical simulation for dynamic characteristics of the flow field of a novel twin screw kneader is carried out. The numerical simulation model of twin screw kneader is established，and the three dimensional，isothermal and steady numerical analyses of non newtonian fluid are presented based on computational fluid dynamics(CFD)theory，and the characteristics under the conditions of different speeds and center distances，such as the distribution of pressure and velocity field，the maximum shear stress，the mass flow rate and so on，are studied. The research results show that：with increasing speed，the maximum flow pressure，the mass flow rate and the maximum shear stress increase; the maximum shear stress increases first and then decreases with increasing of center distance of the screw rotors，while the mass flow rate increases with increasing of center distance; but when the center distance reaches a certain degree，the mass flow rate is negative and the material appears serious reflux which can make the kneader stop working. The results provide a theoretical basis for performance prediction and reasonable designing for the novel twin screw kneader.