To realize efficient operation, the production organization constraints of ironmaking/steelmaking interface, desulphorization basic oxygen furnace and decarburization basic oxygen furnace, refining equipment and casting/rolling interface of typical steel production process A are analyzed. Order planning model of iron and steel enterprises considering production organization constraints is established. The scheduling compact and coordination and the optimization of commissioning date of different production lines are fully considered in the model. Then, the model is solved by tabu search. Finally, three different sizes of actual production contracts which are randomly selected from the steel plant A are simulated. The results prove the presented model and algorithm can harmonize and optimize the production effectively and also realize the process running efficiently.