The circulating cooling water systems of heat transfer equipment generates dirt easily in high temperatures. Dirt will not only reduce thermal efficiency of heat exchange equipment, but also affect the equipment safety. This paper sets up a platform of miniature water cycle based on the real structure of industrial circulating water, uses high-frequency pulse treatment method to act on calcium carbonate in circulating cooling water of manual configuration, observes the impaction of blank group and different frequencies of high frequency electromagnetic pulse groups on fouling in cooling water, and monitors the thermal resistance of cooling water by a designed thermal resistance monitoring system. The results show that the high-frequency electromagnetic pulse treatment plays a very good anti-scaling effect on circulating cooling water, because both the conductivity decline trend and pH rising trend of water becomes slow. According to the thermal resistance data of analog exchanger, thermal resistances of high frequency processing groups are less than that of blank group. Moreover, it further confirms the important role of anti-scaling for high-frequency electromagnetic pulse.