Railway station building is a kind of special tall space building with large construction amount, high frequency usage and huge lighting energy consumption. There are abundant sunshine resources in alpine regions in China. In the design of railway stations, natural light should be fully used to create a good architectural light environment, reduce indoor lighting energy consumption, and achieve the purpose of protecting the ecological environment in alpine regions. According to the local climate conditions, this paper uses the parametric software Rhino to simulate the dynamic daylighting of railway station buildings in alpine regions. It is found that there are some problems in the use of natural lighting, such as low lighting uniformity, overexposure and glare. To address these issues, the optimization measures are put forward: the effective daylighting in the middle of the station building can be improved by controlling the effective depth of daylighting or setting high side windows; the illumination near the window can be effectively controlled by properly adjusting the light transmittance of the low side window to prevent overexposure; the glare can be prevented and the light environment comfort can be improved by using adjustable photosensitive horizontal sunshade or curtain; the waiting hall can obtain good daylighting self-sufficiency when the light transmittance of high side window reaches above 0.75.