Assessing CO₂ storage capacity in saline aquifers is fundamental to supporting China’s carbon neutrality goals. The Sichuan Basin, an important oil and gas production area in southwest China, lacks in-depth quantitative research on CO₂ storage potential in its deep saline aquifers. The Leikoupo Formation(T₂l) is a high-quality brine reservoir within the Sichuan Basin, with its fourth(T₂l⁴), third (T₂l³), and first(T₂l¹) members identified as target reservoirs for CO₂ sequestration. This study utilizes an analytical solution to assess overpressure induced by multiwell simultaneous injection, and applies the MATLAB-based script CO2BLOCK to evaluate the CO₂ storage potential of deep saline aquifers in the Leikoupo Formation. Results show that under a 30-year continuous CO₂ injection scenario, the CO₂ storage capacity of the Leikoupo Formation reservoir in the Sichuan Basin is 0.83 Gt, with the fourth member showing the highest capacity and the first member the lowest. The maximum sustainable injection rates per well for the fourth, third and first members are 0.550 Mt/a, 0.051 Mt/a and 0.054 Mt/a, with corresponding maximum sustainable overpressures of 3.09 MPa, 5.67 MPa and 6.55 MPa, respectively. The optimal economic configurations (number of wells, well spacing in kilometers) for T₂l⁴, T₂l³ and T₂l¹ are (16, 17) (20, 17) and (16, 19), respectively, with storage capacities of 0.50 Gt, 0.07 Gt and 0.04 Gt under these configurations.