This investigation examines stability challenges in dissolution zones using chamber solution mining at Pengshan Tongle glauberite mine. Through integrated laboratory leaching experiments and FLAC3D finite element modeling, we systematically analyze volume variations of dissolved materials and establish 3D numerical simulations to characterize stress fields, displacement patterns, plastic zone distributions, and surface subsidence. Experimental data reveal that dissolution shrinkage increases proportionally with glauberite content and inversely with ore particle size. Numerical simulations demonstrate: (1) Dissolution contraction ratio critically influences zone stability; (2) Post-leaching bodies exhibit 3.25MPa vertical stress versus 13MPa in intact columns; (3) Roof-connected scenarios show 7mm roof subsidence (7.7mm surface), while non-connected cases display 37.7mm roof displacement (34.5mm surface). The results confirm that roof-connected leached material maintains effective support, ensuring overall stability, whereas non-connected conditions pose potential risks. These findings provide crucial insights for ensuring long-term operational safety in evaporite mining engineering.