Combined microwave-convection drying characteristics are investigated by numerical simulation. Combined microwave-convection drying has advantage of swift drying and sterilization. Based on qualitative analyses on the mechanism of combined microwave-convection drying, the differential equations are established and the numerical simulation method is described. The humidity, vapor pressure and temperature, along the radius in a spherical pill, are calculated by the numerical simulation during drying process. The calculation results show the relationship between humidity, vapor pressure, temperature and drying time, and that drying process is greatly influenced by input microwave power. The calculation results are good consistent with the experimental datum.