Implications of Serial Analysis of Gene Expression for Cancer Research
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摘要:
基因表达系列分析(serial analysis of gene expression, SAGE)是一种快速分析基因表达信息的技术.它不但能快速、详细地分析成千上万个基因,还能发现新基因,因此是基因表达定性和定量研究的一种新的有效手段.近年来此技术广泛应用于肿瘤的研究,了解肿瘤发病机制,识别诊断和治疗肿瘤的新基因.可以预测SAGE在肿瘤研究和诊断过程中的应用将会对肿瘤的认识和治疗产生深远的影响.
Abstract:
Serial analysis of gene expression (SAGE) is a powerful technique designed to analyze the information of gene expression. It can not only immediately analyze thousands of genes in detail, but also find new genes. Therefore SAGE is an effective tool of qualitative and quantitative research for gene expression. Recently the SAGE method is widespread applied in cancer research, understanding pathways involved in tumorigenesis and identifying novel diagnostic and therapeutic targets. It is implied that SAGE in implications for cancer research, diagnostic and targeting process will have a great impact on cancer research.