With an inelastic dynamic analysis program developed by the authors, seismic response analysis of regular RC frames designed to Chinese codes in different earthquake fortification zones are carried out. The results indicate that the displacement responses of structures are improved due to the more rigorous limitation on the inter-story drift under frequent earthquakes in the revised codes. The frames in seismic-intensity-9 zone designed to the former codes and the revised codes form plastic energy-dissipated mechanisms mostly With beam hinges, which can satisfy the requirement of seismic performance expectably. The frame in seismic-intensity-8 zone designed to the former code forms a plastic energy- dissipated mechanisms mostly with column hinges and shows a risk of occurrence of story-sway mechanism, while the frame in seismic-intensity-8 zone designed to the revised codes exhibits a relatively improved seismic performance but still with excessive column hinges, which suggests a need to further increase the column moment amplification measures for this kind of frames. The frame in seismic-intensity-7 zone shows a somewhat improved seismic performance than the frames in seismic-intensity-8 zone, but the protection to columns by the seismic measures is sill insufficient, which indicates that the column moment amplification measures for this kind of frames should be enhanced further.