Due to the bad heat dissipation of the existing heat dissipation structure of DC-DC and IPU for hybrid electric vehicle(HEV), the temperature of DC-DC and IPU will rise during the running process, which in turn decreases the stability and reliability of the hybrid electric system. Aiming at this problem, a three-dimensional, transient heat dissipation model is built for DC-DC and IPU heat dissipation structure based on the mass, momentum and energy conservation equations. By using computational fluid dynamics (CFD) software, flow field and temperature field of DC-DC and IPU heat dissipation structure are numerically simulated. Based on the simulation, and combined with heat transfer theory, an improvement scheme of heat dissipation structure is proposed. The simulation results and experiment results of thermal performance and temperature rise show that the improvement scheme can improve the thermal performance, and decrease the temperature rise of DC-DC and IPU effectively, thus satisfy the application requirements in HEV.