高强度皮秒电场脉冲无创治疗肿瘤天线设计
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国家自然科学基金资助项目(50637020,50877083)


Antenna design for non-invasive tumor treatment with high-intensity picosecond electric pulse
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    摘要:

    高强度电场脉冲的脉宽从纳秒级减小到亚纳秒级甚至皮秒级宽度,将使得电场脉冲对生物体结构和功能的影响研究进入新的领域。根据椭球的几何特性,提出一种由椭球面反射器和单圆锥辐射器组成的冲激脉冲辐射聚焦天线,天线可以把高强度皮秒级电场脉冲无创伤地传输至浅层生物组织处。通过高强度电场脉冲的作用来诱导肿瘤细胞凋亡并起到杀伤作用,从而实现肿瘤的无创治疗。仿真结果表明超短时电场脉冲在靶点位置能形成有效的聚焦,并具有很高的幅值,增益和电场方向图在频带内变化稳定,同时,天线性能指标电压驻波比小于2,反射损耗小于-10 dB,满足超宽带时域天线的设计要求。

    Abstract:

    By reducing the pulse width of high intensity electric field from nanosecond to sub-nanosecond or picosecond level,it will lead the research of pulses on the structure and function of organisms to a new field. Based on the geometry characteristics of ellipsoid,an Impulse Radiating Antenna composed of an ellipsoidal reflector and a cone radiator was proposed,which could transform the high-intensity picosecond electric pulses to superficial layer of organisms, then kill tumor cells non-invasively. Simulation analysis shows that the electric field of ultra-short pulses are focusing effectively with high amplitude,while the gain and E-field pattern of the Impulse Radiating Antenna are stable. In addition,the Voltage Standing Wave Radio is less than 2 and the return loss is less than -10dB,all of which meet the design requirements of ultra-wideband time domain antennas.

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姚陈果,龙再全,孙才新,米彦,李成祥.高强度皮秒电场脉冲无创治疗肿瘤天线设计[J].重庆大学学报,2010,33(7):29-34.

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  • 收稿日期:2010-02-25
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