In medical ultrasonic imaging, minimum variance beamforming (MV)can effectively improve imaging resolution, but the contrast is not improved. By considering the low contrast of minimum variance beamforming, a medical imaging method combined minimum variance beamforming and MV-based coherence factor is presented. First, the coherent sum in coherence factor is replaced by the output of MV to obtain weighting factor; and then the factor is used to weight the results of minimum variance beamforming. The simulated results indicate that the proposed method in the aspects of resolution and contrast is better than traditional delay and sum, minimum variance beamforming and medical imaging method combining minimum variance beamforming and coherence factor.