Safe production and procedures at the driving face are restricted in mines of Guizhou province by the long periods required for rock cross-cut coal uncovering in high gas coal seam group. A new method is proposed to solve this problem using high pressure water jet slotting in penetration boreholes. This is proposed to increase the gas desorption rate and reduce drilling hole, which will shorten the cycle of rock cross-cut coal uncovering. Numerical simulation is used to compare the pressure relief effects of different slotting methods in penetration boreholes. The results show that the pressure relief effect of slotting all coal seams is more ideal. Field application indicates that high pressure water jet slotting has good effect of the pressure relief in coal seam group. The drilling number is reduced by 30, the drilling length is shortened by 610 m and the standard time of gas pre-pumping decreases by 39 days.