Xinkaitian area is located in the eastern margin of the central Kangdian Axis. Four uranium mineralization points in Dongguoping, Pingjie, Zhongliangzi and Dayandong, and a lot of abnormal points have been found.Special geological survey, ground gamma spectrometry survey, trough exploration and pit tunnel exposure, sample analysis and other work were carried out in this area, and in combination with typical uranium mineralization of Zhongliangzi and Pingjie village, the characteristics of uranium mineralization in this area were analyzed. The results show that the carbonaceous slate and carbonaceous phyllite in the Heishan formation and Qinglongshan formation are the main ore-bearing horizons(average uranium contentis 7.5×10^-6 to 7.9×10^-6);Laojiezi fault and its secondary faults are the controlling structure of the from area;the hydrothermal alteration related to mineralizationare developed, such as silicification, sericitization and chlorolization. The authors think that uranium mineralization is controlled by stratum and lithology,structure,hydrothermal alteration, and with the rich mineralization information in the zone between the Laojiezi fault and Damayao fault and good magmatic, tectonic and hydrothemal conditions, the area should be the most advantageous metallogenic section in Xinkaitian area and the key area for future prospecting.