The increase of international students created new problems for the higher education in recent China. The full English course of water supply and drainage system in buildings is a major course for international students in the area of civil and environmental engineering. Compared to traditional Chinese teaching method, the diverse background, different expectations, distinct water supply and drainage system and lack of clear full English teaching method make the course teaching cannot meet the need of international students training. With the teaching practice, the author suggests introducing full English textbook, standardizing terminology, clarifying teaching tasks and establishing course contents, using the modern teaching method, enhancing subject construction and improving the internationalization of course teaching. That provides guarantee to the talent training objective for international students.