The background of teaching reform of high-rise building structure design course was analyzed. In the modularization teaching reform process, the orientation of engineering ability was presented, the high-rise building structure design was set as a module, the basic idea and contents of the module were discussed, and the teaching plan and implementation of the module were put forward. In the teaching process, we should pay attention to the interpretation of relevant design specifications and reinforce the evaluation on students from aspects of theoretical study, independent study and practical design.