To improve the teaching effect of concrete structure, the necessity of the teaching reform in the concrete structure course was analyzed. According to the characteristics of concrete structure course,the quaternity inquiry teaching method of preview teaching, students self-learning, preview tutoring, summary teaching was creatively put forward, and the security measures of the teaching effect was pointed out. At last, combined with the practice application, the paper elaborated the teaching effect of the quaternity inquiry teaching method to provide reference for teaching reform of concrete structure course in other schools.