The reform of civil engineering materials course in civil engineering specialty of Tongji Zhejiang College was introduced in this paper. In accordance with their cultivation objectives, specialized characteristic and the students' situation, the reform was carried out from the several aspects including teaching content, teaching method, experiment and curriculum testing pattern. Teaching contents were focused on the properties and applications of building structure materials with the update of content and the introduction of advanced materials. The course was taught by the teaching methods of the multimedia course ware and case teaching method in combination with strengthening the interaction between teaching and study and controlling the learning process. A new experiment teaching mode was formed, namely the coordination between the theoretical and experimental teaching in terms of contents and teachers, the concurrence of basic, comprehensive, and multiple solutions experiments, the combination of video, on-site demonstration and practical operation, and the experiment examination. A comprehensive evaluation method was taken as the curriculum testing pattern.