In order to solve the problems in the actual employment of water supply and drainage engineering and the existing cultivating patterns of school-enterprise cooperation, the cultivating patterns of technical applied type for water supply and drainage engineering based on school-enterprise cooperation was put forward. The cultivating patterns was based on the premise of the school-enterprise cooperation, and the goal was to cultivate high-quality technical talents. The establishment of talents training mechanism of school-enterprise cooperation, including the construction of work organization and management system, the reform of curriculum system, teaching methods and content, teachers structure and talent-training model, the construct of diversified platforms, and the establishment of comprehensive evaluation index system in the cultivating patterns were discussed.