With the help of NVivo 8.0 in managing and coding original resources, this paper adopts original interview data. By using qualitative analysis method based on the Grounded Theory, the paper concludes three factors of science and engineering university students' cognition about humanistic quality, including humanistic spirit, humanistic thought and humanistic methods. The cognition of humanistic quality of the students reflects their reflection and demand of humanistic quality. However, reflecting on the present concept of humanistic quality education of science and engineering students, it's lost many core contents of humanistic quality. During the humanistic quality education reform process, we must first make up these lost humanistic quality education concepts. This study is "student-oriented", standing on the demand side of humanistic quality education to do research, which is important for supply-side reform of humanistic quality education.