The key point and foundation of the construction of first-class universities is discipline construction. Under the background of construction of first-class universities, analyzes the development of humanities and social sciences through the status quo of first-class discipline construction, construction points, and development policies of discipline. Analyze the internal causes of the development of humanities and social sciences from the conditions of teachers, researchers and top level design for discipline construction. To change the development of humanities and social sciences, we should take measures such as enhancing the practicality of the subject, following the inherent legitimacy of discipline development, improving external incentives and strengthening the top-level design of discipline development.