Seismic design of building structures is a strongly comprehensive professional course of the structural engineering division which covers disciplines such as steel and concrete structures, structural mechanics, geology, and seismic engineering. Compared to other professional courses with rather singular knowledge systems, this course requires much more for the integrity of knowledge. The article focuses on the case project teaching approach, explaining why the method was proposed, its characteristics, and its specific requirements. It also provides some advice about the application of this new approach on actual courses. We sincerely hope that this article can be of help in the widespread application of the case project teaching approach.