Civil engineering is a practical subject, and therefore, the cultivation of civil engineering talents needs to combine with practice. There is a significant meaning for improving cultivation quality in the integration of production, teaching and research. Combining with more than ten years teaching experiences, the civil engineering talents training model with integration of production-university-research has been created. Colleges need to cultivate more inter-disciplinary talents who can meet the needs of society, and corporations have to put forward professional and technical requirements according to their needs. Only through the way to building a system of production-university-research cooperative education that integrates "collaborative education", "collaborative teaching", and "collaborative innovation" by colleges and corporations together, can it promote the cultivation of civil engineering talents in the integration of production-teaching-research effectively.