This article analyzes the problems in the training of engineering graduate students based on the background of emerging engineering construction. Taking biomedical engineering as an example and ideological and political education as the initial intention, by building discipline integration tutor groups, taking the integrated teaching of postgraduate innovation and dual practice as the main carrier, the student-teacher collaboration platform, medical-enterprise cooperation platform, science-enterprise co-creation platform, and teaching-research platform as a support, and the "discipline, investigation, lecture, exchange, evaluation, supervision" teaching supervision system as a guarantee, we explore the teaching reform of engineering graduate students. The full coverage and integration of students' knowledge structure, interest in learning, learning ability, thinking mode have realized, and the emerging engineering graduate education system that is full of vitality, multi-level, optional, and with professional characteristics has formed.