The seismic courses of engineering structure are comprehensive professional courses of civil engineering. The teaching object is the senior undergraduate students majoring in civil engineering. There are many theoretical points in these courses, involving the latest development of structural seismic technology. Limited to class hours and teaching funds, experimental teaching is generally limited to the mechanical property experiment of beam and column members under tension, compression, bending, torsion and other loads. Structural dynamic experiments are rarely conducted, such as structural dynamic characteristics test, component energy dissipation capacity test, structural seismic responses, and other experiments. This paper introduces the present situation of the experimental teaching of engineering structure seismic courses, analyzes on the shortcomings of the existing experimental teaching contents, puts forward some suggestions on setting up the experimental courses related to structural seismic performance, and the experimental courses of mechanical properties of building and bridge seismic isolation devices, and carries out the course building from the aspects of compiling the teaching syllabus, experimental instructions, teaching handouts, preparing the template of experimental reports, and teaching practice. Through three years of teaching practice, combined with the latest engineering practice and classroom teaching, reform of the experimental teaching has achieved good teaching effect. Students have fully understood all kinds of seismic reduction and isolation devices, the newest structural design concepts and new structural systems, and have received standardized experimental operation skills training. This has laid a good foundation for students to quickly understand engineering construction procedures and standards after employment, or to continue their further study.