The development of modern education encourages enterprises to participate in the training of students in universities, deepen the integration of industry and education, and cultivate high-quality applied talents needed by the industry. With the promotion and application of new materials, new energy and new technologies in the engineering management industry, the cultivation of engineering management professionals requires the integration of industry and education. Industry, university, research, and application collaborative education is an important way to integrate industry and education. However, there are still many deficiencies in this mechanism, for example, the professional training program and curriculum system are difficult to meet the needs of industry development; the mobility of talents between schools and enterprises is low; the interests of schools and enterprises cannot be taken into account; the development motivation is lacking and the development mechanism is not perfect, etc. To solve these deficiencies, this study proposes the following methods, for example, establish an undergraduate curriculum system based on market demand; establish a teacher system for the flow of talents between schools and enterprises; establish a 3+1 training system that deeply integrates theory and practice; establish a whole process and diversification supervision and evaluation system, as well as an educational platform for the common progress of schools and enterprises. Meanwhile, it is necessary to establish a motivation mechanism for the participation of universities and enterprises; a guarantee mechanism for the smooth implementation of collaborative education projects; an incentive mechanism for stimulating the participation of all parties; and an effect evaluation and feedback mechanism. Finally, an industry, university, research, and application collaborative unified platform sustainable operation mechanism will be formed. Therefore, the government should increase its support for industry, university, research, and application, and continue to encourage construction companies to increase investment in university education by improving the law and solidifying the legal foundation of the platform. At the same time, financial subsides and tax incentives should be given to relevant groups, a special development plan for engineering management industry colleges should be implemented, and the university’s positioning should be clarified to gradually form a benign development mechanism.