Under the guidance of the national "double carbon" strategy and high-quality development goals, the coordinated development of intelligent construction and new building industrialization has become an inevitable choice for the transformation and upgrading of China’s construction industry. The corresponding demand for intelligent construction talents is urgent. It has become an important task and challenge for relevant colleges and universities to cultivate innovative intelligent construction talents to adapt to the future development needs of the construction industry and meet the needs of industrial transformation and upgrading. Local colleges and universities are important forces to cultivate intelligent construction talents. However, in the process of intelligent construction talent training, local colleges and universities generally have difficulties such as the lack of engineering practice experience in the teaching staff, the difficulty of setting up a multi-disciplinary interdisciplinary curriculum system, the difficulty of multi-professional organization and coordination, and the difficulty of talent introduction and training. It is urgent for local colleges and universities to solve the problem of how to base on their own school running characteristics, make full use of superior resources to overcome the above difficulties, take students as the center, reasonably position talent training objectives, refine distinctive school running characteristics, and establish a high-quality talent training system. Focusing on improving students’ comprehensive ability and professional competence, the "one center, three synergies" talent training system for intelligent construction professionals, which is driven by "Modern Industry College", "Virtual Teaching and Research Office" and "Engineering Research Center", is an effective exploration of the pain points of intelligent construction talent training in local colleges and universities. Taking the specific practice of the "one center, three synergies" intelligent construction professional training system of Inner Mongolia University of Science and Technology as an example, this paper expounds the connotation, characteristics and specific implementation path of the system, with a view to providing referential experience for the construction of intelligent construction specialty, the upgrading and transformation of civil engineering specialty, talent training and the collaborative education of schools and enterprises in other local universities.