Engineering characteristic guided courses reflect the training objectives of applied talents and help improve the core competitiveness of students in related majors. As one of the representative courses, the course of introduction to architectural engineering has been opened in several majors such as housing management and public management. It can provide non-engineering students with necessary basic engineering theory, but there are also many contradictions that need to be resolved in experimental teaching. On the basis of defining the orientation and characteristics of the course, the necessity of carrying out virtual simulation experiment teaching is systematically analyzed. Based on the requirements of engineering management professional practice ability outline, the teaching objectives of virtual simulation experiment teaching are put forward. To achieve teaching objectives, a virtual simulation comprehensive practical teaching mode with three levels of content: subject general education, professional improvement, and innovative design is designed, and the process assessment of practical teaching is strengthened. The questionnaire survey and quantitative analysis are conducted to evaluate the implementation effect. The teaching mode of virtual simulation experiment well meets the requirements of the professional ability outline of engineering management, which can provide reference for the teaching of engineering characteristic guidance courses in relevant colleges and universities.