Fluid network for transportation and distribution is a core course of building environment and facilities engineering. It is a technical basic course for engineering students to learn and master the basic knowledge and design methods in the process of various fluid transmission and distribution. Taking the opportunity to further deepen the undergraduate teaching reform and connotation construction of Dalian University of Technology, and comprehensively improving the quality of talent training, the course resource platform is reformed in view of the deficiencies in the fluid network for transportation and distribution course. In combination with the construction experience of the first batch of national first-class courses, taking students as the center, advocating learning by doing through task-oriented approaches, learning by discussing basic knowledge, and learning by analyzing engineering cases, a virtual-actual interactive teaching method is proposed, and an entity platform of complex fluid network is constructed. At the same time, the corresponding simulation platform is customized, and a virtual-actual interactive platform of simulation, regulation and data collection is established. Online teaching completes the customization of data model and some simulation modules. Offline, combined with the engineering test-bed, the virtual-real process of self-built platform and regulation is actually completed, and a teaching platform integrating algorithms, software simulation and engineering test is built. Students’ interest in active learning is stimulated, their subjective initiative in learning is mobilized, their innovative thinking is developed, and their innovation and practical abilities are cultivated. We practice scientific research to feed teaching, transform scientific research results into teaching content, and refine the main points of the course from actual engineering and scientific research problems, which strengthens the breadth and depth of the course content. It help students establish the concept of pipe network system with a certain degree of complexity, which is challenging and exercises students’ self-learning and cooperation abilities. The teaching design promotes the deep integration of modern information technology with education and teaching, continuously improves the reform of teaching quality monitoring and guarantee system, and improves the construction of practical teaching system.