The nation clearly considered integration between production and education as the major steps of the reform and development of higher education. In this context, for the problems of college-enterprise cooperation in urban and rural planning major from application-oriented institutions, this paper puts forward the college-enterprise cooperation of urban and rural planning Multinity Integration including teachers, students, enterprises, local governments, vocational training institutions in the perspective of integration between production and education. Depending on central platform of integration between production and education, the research built up cooperative education environment, optimizing the curriculum system and practical teaching system by revising the program of cultivating talents with college and enterprise cooperation, optimizing and innovating the “4+1” in urban and rural planning college-enterprise cooperative talents cultivating model, finally building up the talents cultivating model of integration between production and education of “3+1+1” in urban and rural planning and college-enterprise cooperation.