Local colleges have long been under the influence of regional culture, it is the foundation of the characteristic development of local colleges. The paper explore the main problems existing in the process of characteristic running, analyzes the main influence of regional characteristic culture. It is based on ecological niche theory, research local colleges how to be absorbed regional cultural elements in the process of cultivate distinctive talents,and improve the quality of education through inheriting regional culture. Local colleges should renew the concept of talent training, reconstruct the characteristic curriculum system, expand the way of characteristic education, build the characteristic education platform, implement the characteristic education model.