The applied talent is one of major talent gaps currently. However, the traditional teaching methods cannot meet the needs of cultivating applied technical talents. Classroom teaching reform is an important link in improving applied talent-cultivation system. In this paper, Characteristics of applied undergraduate students and problems of their classroom teaching are analyzed first, and four key problems in classroom teaching process are put forward. Based on these four problems and followed the criteria of golden course, the research and practice on blended learning based on SPOC is carried out with the < soil mechanics> course as an example. Contemporary course characteristics are discussed, teaching process and examination criteria are designed, students’scores are analyzed and teaching review is conducted. The practice shows that course difficulty is increased effectively without the increase of class hours after blended learning, study initiatives are improved and good effects have been got. Aiming to provide application-oriented universities a reference of developing blended learning with SPOC and a better practice of “student-centered, outcome-based and ability oriented “teaching concepts.